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Information About 21 C.R.F. § 589.2000 Taken from FDA Guidelines

FDA regulation 21 C.F.R. § 589.2000 is designed to prevent the establishment and amplification of Bovine Spongiform Encephalopathy (BSE), sometimes referred to as "Mad Cow Disease" through animal feed. The regulation prohibits the use of certain proteins derived from mammalian tissue in feeding ruminant animals. Certain products, however, are exempt from the regulation.

The Following Protein Products Derived from Mammals are Exempt:

  • Blood and blood products
  • Milk products (milk and milk proteins)
  • Gelatin
  • Pure porcine (pork) or pure equine (horse) protein
  • Inspected meat products, such as plate waste, which have been cooked and offered for human food and further heat-processed for animal feed
The Following Non-Mammalian Protein Products are Exempt:
  • Poultry
  • Marine (fish)
  • Vegetable
The Following are Also Exempt Because They are Not Protein or Tissue:
  • Grease
  • Tallow
  • Fat
  • Oil
  • Amino acids
  • Dicalcium phosphate
The exempted products listed above are not prohibited by 21 C.F.R. § 589.2000 for use in feeding ruminant animals. All mammalian protein that is not exempted is referred to by the FDA as "prohibited material". Prohibited material and feeds containing prohibited material are prohibited for use in feeding ruminant animals. Ruminant animals are animals with a four-chambered stomach such as cattle, sheep, goats, bison, elk and deer.
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